Article
Oxidative DNA damage and total antioxidant status in serum of patients with esophageal squamous cell carcinoma.
Hepato-gastroenterology - 1 Sept 2007
Diakowska Dorota, Lewandowski Andrzej, Kopeć Wacław, Diakowski Witold, Chrzanowska Teresa
Abstract excerpt
BACKGROUND/AIMS: Oxidative stress is connected with activation of somatic mutations and rates of cell proliferation existing in cancer tissue. High level of reactive oxygen species is a mutagenic factor for DNA damage. Antioxidants are the components of the cellular defense mechanism against reactive oxygen molecules. The aim of our study was to analyze DNA peroxidation products' concentration and total...
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