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Article

Genetic changes of hOGG1 and the activity of oh8Gua glycosylase in colon cancer.

European journal of cancer (Oxford, England : 1990) - 1 Feb 2001

Park Y J, Choi E Y, Choi J Y, Park J G, You H J, Chung M H

Abstract excerpt

oh8Gua glycosylase repairs DNA by removing oh8Gua, a highly mutagenic oxidative DNA adduct. Recently, the gene for human oh8Gua glycosylase (hOGG1) was cloned and several mutational types have been reported. However, the implications of such mutations in human cancer have not been clearly demonstrated. To test the involvement of hOGG1 mutation in colon carcinogenesis, we analysed the genetic changes of hOGG1 and...

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PMID: 11239755
DOI: 10.1016/s0959-8049(00)00388-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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