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Article

Enhancement of lung carcinogenesis initiated with 4-(N-hydroxymethylnitrosamino)-1-(3-pyridyl)-1-butanone by Ogg1 gene deficiency in female, but not male, mice.

The Journal of toxicological sciences - 1 Apr 2009

Igarashi Maki, Watanabe Manabu, Yoshida Midori, Sugaya Kouichi, Endo Yoshifumi, Miyajima Nozomi, Abe Masayoshi, Sugano Sumio, Nakae Dai

Abstract excerpt

The present study was conducted to assess involvement of oxidative stress in lung adeno-carcinogenesis, using mice deficient in the 8-hydroxyguanine DNA glycosylase 1 (Ogg1) gene encoding an enzyme that repairs an oxidative DNA injury 8-oxoguanine (8-oxoG). Furthermore, for comparison with the hu...

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PMID: 19336973
DOI: 10.2131/jts.34.163

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19336973-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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