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Article

Pharmacogenetics of Tenofovir Treatment

1 Oct 2009

Abstract excerpt

Tenofovir disoproxil fumarate (TDF) is a nucleotide analog used as part of HIV therapy. Its favorable profile in terms of high efficacy, low toxicity and once-daily dosing makes TDF one of the most attractive antiretroviral agents, and therefore, it is widely used. However, cases of kidney tubular dysfunction have been reported and concern exists regarding the long term use of TDF. Owing to the high...

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PMID: 19842939
DOI: 10.2217/pgs.09.115

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