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Article

A Single-Nucleotide Polymorphism in ABCC4 Is Associated with Tenofovir-Related Beta2-Microglobulinuria in Thai Patients with HIV-1 Infection.

PloS one - 1 Jan 2016

Likanonsakul Sirirat, Suntisuklappon Bussakorn, Nitiyanontakij Ravee, Prasithsirikul Wisit, Nakayama Emi E, Shioda Tatsuo, Sangsajja Chariya

Abstract excerpt

BACKGROUND: In Thailand, the combined generic anti-retroviral drug stavudine/lamivudine/nevirapine (d4T/3TC/NVP) has been used to treat human immunodeficiency virus (HIV)-infected individuals since 2001. Due to relatively frequent adverse effects, d4T gradually has been replaced with tenofovir disoproxil fumarate (TDF). Although the frequency of adverse drug effects with TDF is lower than that with d4T, TDF is...

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Source

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Identifiers

PMID: 26807589
DOI: 10.1371/journal.pone.0147724
PMCID: PMC4726597

Genes

ABCC4
ABCC2

Variants

rs717620
rs717620

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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A Single-Nucleotide Polymorphism in ABCC4 Is Associated with Tenofovir-Related Beta2-Microglobulinuria in Thai Patients with HIV-1 Infection.PMID 26807589Read ↗

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