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Article

ABCC4 single-nucleotide polymorphisms as markers of tenofovir disoproxil fumarate-induced kidney impairment.

The pharmacogenomics journal - 1 Oct 2021

Cheli Stefania, Baldelli Sara, De Silvestri Annalisa, Fusi Marta, Minisci Davide, Gervasoni Cristina, Cattaneo Dario, Clementi Emilio, Meraviglia Paola, Montrasio Cristina

Abstract excerpt

Recently, the use of antiretroviral drug tenofovir disoproxil fumarate (TDF) is increased, thanks to the new co-formulation with doravirine, the availability of booster-free regimens, and its advantageous lipid-lowering effect. The aim of our study was to identify genetic markers that contribute to assess the risk of TDF-related renal toxicity. We have retrospectively investigated, in 179 HIV positive patients...

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PMID: 33850298
DOI: 10.1038/s41397-021-00235-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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