Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ABCC2*1C and plasma tenofovir concentration are correlated to decreased glomerular filtration rate in patients receiving a tenofovir-containing antiretroviral regimen.

The Journal of antimicrobial chemotherapy - 1 Aug 2014

Manosuthi Weerawat, Sukasem Chonlaphat, Thongyen Supeda, Nilkamhang Samruay, Sungkanuparph Somnuek

Abstract excerpt

OBJECTIVES: To study the correlations of genetic variants of tenofovir tubular transporters, plasma tenofovir concentrations and clinical factors with decreased glomerular filtration rate in HIV-infected patients who received tenofovir. METHODS: A total of 117 HIV-1-infected patients were administered antiretroviral therapy with tenofovir/lamivudine/efavirenz. Two single nucleotide polymorphisms (SNPs), ABCC2*1C...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alkynes
Share to Benzoxazines

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Creatinine

Share to Cyclopropanes

Share to Glomerular Filtration Rate

Share to Multidrug Resistance-Associated Protein 2

Share to Organophosphonates

Share to Tenofovir

Source

Identifiers

PMID: 24788661
DOI: 10.1093/jac/dku129

Genes

ABCC2
ABCB1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ABCC2*1C and plasma tenofovir concentration are correlated to decreased glomerular filtration rate in patients receiving a tenofovir-containing antiretroviral regimen.PMID 24788661Read ↗

A Single-Nucleotide Polymorphism in ABCC4 Is Associated with Tenofovir-Related Beta2-Microglobulinuria in Thai Patients with HIV-1 Infection.Semantic proximity Read ↗

Single nucleotide polymorphisms in ABCC2 associate with tenofovir-induced kidney tubular dysfunction in Japanese patients with HIV-1 infection: a pharmacogenetic study.Semantic proximity Read ↗

Influence of <i>ABCC2</i> and <i>ABCC4</i> Polymorphisms on Tenofovir Plasma Concentrations in Thai HIV-Infected PatientsSemantic proximity Read ↗

Clinical pharmacology of tenofovir clearance: a pharmacokinetic/pharmacogenetic study on plasma and urines.Semantic proximity Read ↗

Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202.Semantic proximity Read ↗

Clinical and genetic factors associated with kidney tubular dysfunction in a real-life single centre cohort of HIV-positive patients.Semantic proximity Read ↗

Tenofovir-induced renal tubular dysfunction in vertically HIV-infected patients associated with polymorphisms in ABCC2, ABCC4 and ABCC10 genes.Semantic proximity Read ↗

Pharmacogenetics-based population pharmacokinetic analysis of tenofovir in Thai HIV-infected patients.Semantic proximity Read ↗

Do genetic variations in proximal tubule transporters influence tenofovir-induced renal dysfunction? An exploratory study in a Ghanaian population.Semantic proximity Read ↗

Genetic variants of ABCC10, a novel tenofovir transporter, are associated with kidney tubular dysfunction.Semantic proximity Read ↗

Pharmacogenetics of Tenofovir TreatmentSemantic proximity Read ↗

Evaluating the association of single-nucleotide polymorphisms with tenofovir exposure in a diverse prospective cohort of women living with HIV.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.