Article
Pharmacogenetics of tenofovir drug transporters in the context of HBV: Is there an impact?
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Jun 2024
Cusato J, Manca A, Palermiti A, Mula J, Antonucci M, Chiara F, De Nicolò A, Lupia Tommaso, Stroffolini Giacomo, Boglione L, D'Avolio A
Abstract excerpt
BACKGROUND: Current treatments for chronic hepatitis B management include orally administered nucleos(t)ide analogues, such as tenofovir (TDF), which is an acyclic adenine nucleotide analogue used both in HBV and human immune deficiency virus (HIV). The course of HBV infection is mainly dependent on viral factors, such as HBV genotypes, immunological features and host genetic variables, but a few data are...
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