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Article

Tenofovir-induced renal tubular dysfunction in vertically HIV-infected patients associated with polymorphisms in ABCC2, ABCC4 and ABCC10 genes.

The Pediatric infectious disease journal - 1 Oct 2013

Giacomet Vania, Cattaneo Dario, Viganò Alessandra, Nannini Pilar, Manfredini Valeria, Ramponi Giulia, Clementi Emilio, Zuccotti Gian Vincenzo

Abstract excerpt

Tenofovir disoproxyl fumarate is a known cause of kidney tubular dysfunction in HIV-infected patients. Recent studies reported significant association between specific allelic variants in ABCC2, ABCC4 and/or ABCC10 genes and the development of kidney tubular dysfunction in HIV-infected adults. We describe the first 2 cases of vertically HIV-infected patients affected by kidney tubular dysfunction associated with...

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Source

Identifiers

PMID: 24067562
DOI: 10.1097/INF.0b013e31829e6c9c

Genes

ABCC10
ABCC2
ABCC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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