Article
A powerful genome-wide feasible approach to detect parent-of-origin effects in studies of quantitative traits.
European journal of human genetics : EJHG - 1 Mar 2010
Belonogova Nadezhda M, Axenovich Tatiana I, Aulchenko Yurii S
Abstract excerpt
There is currently a lot of interest in the role of genomic imprinting in mammalian development. Many human diseases, such as cancer, obesity, diabetes and behavioral traits, may be related to imprinted genes. When searching for genes related to complex disorders, the power of genome-wide association analysis can be improved by introducing parent-of-origin effects into the analyses. For quantitative traits,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
