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Article

A novel approach to detect parent-of-origin effects from pedigree data with application to Beckwith-Wiedemann syndrome.

Annals of human genetics - 1 Nov 2007

Shete Sanjay, Elston Robert C, Lu Yue

Abstract excerpt

The parent-of-origin phenomenon in humans is now well recognized, and the deregulation of imprinted genes has been implicated in a number of human diseases. Recently, several linkage analysis methods have been developed to allow for parent-of-origin effects in the analysis of pedigree data. However, in general, one does not know a priori if disease-causing loci are imprinted or not. Linkage methods that allow for...

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Identifiers

PMID: 17578507
DOI: 10.1111/j.1469-1809.2007.00378.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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