Article
Generalized gametic relationships for flexible analyses of parent-of-origin effects.
G3 (Bethesda, Md.) - 7 Aug 2021
Reinsch Norbert, Mayer Manfred, Blunk Inga
Abstract excerpt
A class of epigenetic inheritance patterns known as genomic imprinting allows alleles to influence the phenotype in a parent-of-origin-specific manner. Various pedigree-based parent-of-origin analyses of quantitative traits have attempted to determine the share of genetic variance that is attributable to imprinted loci. In general, these methods require four random gametic effects per pedigree member to account...
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