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Article

Genome-wide survey of parent-of-origin effects on DNA methylation identifies candidate imprinted loci in humans.

Human molecular genetics - 15 Aug 2018

Cuellar Partida Gabriel, Laurin Charles, Ring Susan M, Gaunt Tom R, McRae Allan F, Visscher Peter M, Montgomery Grant W, Martin Nicholas G, Hemani Gibran, Suderman Matthew, Relton Caroline L, Davey Smith George, Evans David M

Abstract excerpt

Genomic imprinting is an epigenetic mechanism leading to parent-of-origin silencing of alleles. So far, the precise number of imprinted regions in humans is uncertain. In this study, we leveraged genome-wide DNA methylation in whole blood measured longitudinally at three time points (birth, childhood and adolescence) and genome-wide association studies (GWAS) data in 740 mother-child duos from the Avon...

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Identifiers

PMID: 29860447
DOI: 10.1093/hmg/ddy206
PMCID: PMC6077796

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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