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Article

A statistical test for detecting parent-of-origin effects when parental information is missing.

Statistical applications in genetics and molecular biology - 26 Sept 2017

Sacco Chiara, Viroli Cinzia, Falchi Mario

Abstract excerpt

Genomic imprinting is an epigenetic mechanism that leads to differential contributions of maternal and paternal alleles to offspring gene expression in a parent-of-origin manner. We propose a novel test for detecting the parent-of-origin effects (POEs) in genome wide genotype data from related individuals (twins) when the parental origin cannot be inferred. The proposed method exploits a finite mixture of linear...

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PMID: 28862993
DOI: 10.1515/sagmb-2017-0007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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