Exact tests for Hardy-Weinberg proportions.

doi:10.1534/genetics.109.108977

Back to search

Article

Exact tests for Hardy-Weinberg proportions.

Genetics - 1 Dec 2009

Engels William R

Abstract excerpt

Exact conditional tests are often required to evaluate statistically whether a sample of diploids comes from a population with Hardy-Weinberg proportions or to confirm the accuracy of genotype assignments. This requirement is especially common when the sample includes multiple alleles and sparse data, thus rendering asymptotic methods, such as the common chi(2)-test, unreliable. Such an exact test can be...

Topics

Algorithms
Alleles
Diploidy
Heterozygote
Homozygote
Models, Genetic
Monte Carlo Method
Probability

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.