Article
Multi-allelic exact tests for Hardy-Weinberg equilibrium that account for gender.
Molecular ecology resources - 1 May 2018
Graffelman Jan, Weir Bruce S
Abstract excerpt
Statistical tests for Hardy-Weinberg equilibrium are important elementary tools in genetic data analysis. X-chromosomal variants have long been tested by applying autosomal test procedures to females only, and gender is usually not considered when testing autosomal variants for equilibrium. Recently, we proposed specific X-chromosomal exact test procedures for bi-allelic variants that include the hemizygous...
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