Article
Performing the exact test of Hardy-Weinberg proportion for multiple alleles.
Biometrics - 1 Jun 1992
Guo S W, Thompson E A
Abstract excerpt
The Hardy-Weinberg law plays an important role in the field of population genetics and often serves as a basis for genetic inference. Because of its importance, much attention has been devoted to tests of Hardy-Weinberg proportions (HWP) over the decades. It has long been recognized that large-sample goodness-of-fit tests can sometimes lead to spurious results when the sample size and/or some genotypic...
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