Article
Testing Departure from Hardy-Weinberg Proportions.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017
Wang Jian, Shete Sanjay
Abstract excerpt
The Hardy-Weinberg principle, one of the most important principles in population genetics, was originally developed for the study of allele frequency changes in a population over generations. It is now, however, widely used in studies of human diseases to detect inbreeding, population stratification, and genotyping errors. For assessment of deviation from Hardy-Weinberg proportions in data, the most popular...
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