Article
Statistical power of an exact test of Hardy-Weinberg proportions of genotypic data at a multiallelic locus.
Human heredity - 1 Jan 2000
Chakraborty R, Zhong Y
Abstract excerpt
A computer algorithm for numerical evaluation of the statistical power of an exact test of Hardy-Weinberg genotypic proportions (HWP), developed here, indicates that the power is dependent on the number of segregating alleles as well as allele frequencies. While low levels of departure from the null hypothesis are difficult to detect from single-locus data, should such deviation be due to population...
Topics
- Algorithms
- Alleles
- Chromosome Mapping
- Genotype
- Humans
- Models, Statistical
- Numerical Analysis, Computer-Assisted