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Article

Hardy-Weinberg testing of a single homozygous genotype.

Genetics - 1 Jul 2005

Chen John J, Duan Tao, Single Richard, Mather Kristie, Thomson Glenys

Abstract excerpt

No proper statistical test is available for the evaluation of deviation of a single homozygous genotype from Hardy-Weinberg equilibrium (HWE) proportion. We propose a 1-d.f. chi2-test. The power of the proposed test is favorable compared to existing HWE testing procedures. The applications of this test are discussed.

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Identifiers

PMID: 15911570
DOI: 10.1534/genetics.105.043190
PMCID: PMC1451168

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