Hardy-Weinberg testing of a single homozygous genotype.

doi:10.1534/genetics.105.043190

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Article

Hardy-Weinberg testing of a single homozygous genotype.

Genetics - 1 Jul 2005

Chen John J, Duan Tao, Single Richard, Mather Kristie, Thomson Glenys

Abstract excerpt

No proper statistical test is available for the evaluation of deviation of a single homozygous genotype from Hardy-Weinberg equilibrium (HWE) proportion. We propose a 1-d.f. chi2-test. The power of the proposed test is favorable compared to existing HWE testing procedures. The applications of this test are discussed.

Topics

Gene Frequency
Genetics, Population
Genotype
Models, Genetic
Statistics as Topic

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