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Article

Exact test of Hardy-Weinberg equilibrium by Markov chain Monte Carlo.

Mathematical medicine and biology : a journal of the IMA - 1 Dec 2003

Yuan Ao, Bonney George E

Abstract excerpt

The assumption of Hardy-Weinberg equilibrium (HWE) among alleles is of fundamental importance in genetic studies. There are numerous testing methods for it using genotype counts data. The exact test is used when the sample size is not large enough for asymptotic approximations. There are several numerical methods to carry out this test, such as complete enumeration, Monte Carlo and Markov chain Monte Carlo...

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Identifiers

PMID: 14969383
DOI: 10.1093/imammb/20.4.327

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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