Article
An incomplete enumeration algorithm for an exact test of Hardy-Weinberg proportions with multiple alleles.
TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik - 1 Aug 2007
Maurer H P, Melchinger A E, Frisch M
Abstract excerpt
Testing of Hardy-Weinberg proportions (HWP) with asymptotic goodness-of-fit tests is problematic when the contingency table of observed genotype counts has sparse cells or the sample size is low, and exact procedures are to be preferred. Exact p-values can be (1) calculated via computational demanding enumeration methods or (2) approximated via simulation methods. Our objective was to develop a new algorithm for...
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