Article
Class F Thy-1-negative murine lymphoma cells are deficient in ether lipid biosynthesis.
The Journal of biological chemistry - 15 Sept 1990
Stevens V L, Raetz C R
Abstract excerpt
The glycosyl phosphatidylinositol (PI) membrane anchors of several proteins contain 1-alkyl-2-acyl-glycerophosphoinositol. Although this PI analog has never been found free in cells, the presence of "alkyl-PI" as a component of some membrane anchors suggests its existence. The resistance of ether linkages to cleavage by mild alkali treatment was used to detect possible alkyl chains in the [3H]inositol-labeled...
Topics
- Acyltransferases
- Animals
- Antigens, Surface
- Cell Line
- Cell Survival
- Glycerides
- Glycolipids
- Glycosylphosphatidylinositols
- Inositol
- Lymphoma
- Mice
- Microbodies
