Article
Biochemical analysis of glycophospholipids from wild-type mouse lymphoma cells and from Thy-1 negative mutants which do not add glycolipid-anchored proteins.
Indian journal of biochemistry & biophysics - 1 Dec 1990
Gupta D K, Lemansky P A, Tartakoff A M
Abstract excerpt
Thy-1 is a major glycophospholipid (GPL)-anchored protein found on the surface of neurons, epithelial cells, fibroblasts and murine T-lymphomas. Biochemical studies were undertaken to determine if murine T-lymphomas contain glycolipids which may be on the path of GPL-anchor biosynthesis. Biosynthetic labeling experiments on Thy-1-positive (wild-type) cells followed by battery of chemical and enzymatic diagnostics...
Topics
- Animals
- Antigens, Surface
- Carbohydrate Sequence
- Chromatography, Thin Layer
- Glycolipids
- Glycosylphosphatidylinositols
- Lymphoma, T-Cell
- Membrane Glycoproteins
- Mice
- Molecular Sequence Data