Article
Atypical mannolipids characterize Thy-1-negative lymphoma mutants.
Molecular and cellular biology - 1 Aug 1991
Lemansky P, Gupta D K, Meyale S, Tucker G, Tartakoff A M
Abstract excerpt
Essentially all eukaryotic cells, including murine lymphomas, express surface proteins, such as Thy-1, which are anchored by a phosphoinositol mannolipid. Putative mannolipid anchor precursors can be detected in these cells. Six distinct Thy-1-negative lymphoma mutants lack complete mannolipids, and three mutants synthesize atypical mannolipids. The absence of complete mannolipids can account for the lack of...
Topics
- Animals
- Antigens, Surface
- Carbohydrate Sequence
- Cell Line
- Glycolipids
- Glycosylphosphatidylinositols
- Lymphoma
- Mannose
- Mice
- Molecular Sequence Data
- Mutation
- Phenotype