Article
HLA susceptibility genes in celiac disease: genetic mapping and role in pathogenesis.
Gastroenterology - 1 Sept 1993
Sollid L M, Thorsby E
Abstract excerpt
The overrepresentation of particular HLA alleles in patients with celiac disease was first noted two decades ago. Several lines of evidence obtained during the last years strongly suggest that a particular HLA-DQ heterodimer, encoded by the DQA1*0501 and DQB1*0201 genes in cis or trans configurat...
Topics
- Alleles
- Celiac Disease
- Chromosome Mapping
- Genes, MHC Class I
- Genes, MHC Class II
- Genetic Predisposition to Disease
- Humans
