Article
Susceptibility to develop celiac disease is primarily associated with HLA-DQ alleles.
Human immunology - 1 Nov 1990
Spurkland A, Sollid L M, Rønningen K S, Bosnes V, Ek J, Vartdal F, Thorsby E
Abstract excerpt
We have recently reported that the susceptibility to develop celiac disease (CD) seems to be primarily associated to a particular combination of an HLA-DQA1 (DQA1*0501) and an HLA-DQB1 (DQB1*0201) allele: i.e., a particular DQ alpha/beta heterodimer. To investigate whether certain DP alleles might also contribute to the genetic susceptibility, DPA1 and DPB1 genes of 94 CD patients and 132 healthy controls were...
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