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Article

Susceptibility to develop celiac disease is primarily associated with HLA-DQ alleles.

Human immunology - 1 Nov 1990

Spurkland A, Sollid L M, Rønningen K S, Bosnes V, Ek J, Vartdal F, Thorsby E

Abstract excerpt

We have recently reported that the susceptibility to develop celiac disease (CD) seems to be primarily associated to a particular combination of an HLA-DQA1 (DQA1*0501) and an HLA-DQB1 (DQB1*0201) allele: i.e., a particular DQ alpha/beta heterodimer. To investigate whether certain DP alleles might also contribute to the genetic susceptibility, DPA1 and DPB1 genes of 94 CD patients and 132 healthy controls were...

Topics

Alleles
Base Sequence
Celiac Disease
DNA
Disease Susceptibility
Gene Amplification
HLA-DP Antigens
HLA-DQ Antigens
Humans
Molecular Sequence Data
Oligonucleotide Probes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Restriction Fragment Length

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Source

Identifiers

PMID: 1980918
DOI: 10.1016/0198-8859(90)90111-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1980918-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Susceptibility to develop celiac disease is primarily associated with HLA-DQ alleles.PMID 1980918Read ↗

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