Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Synergistic effect of two HLA heterodimers in the susceptibility to celiac disease in Tunisia.

Genetic epidemiology - 1 Jan 1997

Bouguerra F, Babron M C, Eliaou J F, Debbabi A, Clot J, Khaldi F, Greco L, Clerget-Darpoux F

Abstract excerpt

The DR and DQ HLA genotypes of 94 Tunisian children affected with celiac disease are analyzed so that we can gain a better understanding of the HLA component of this disease. All of them carry at least one of two specific heterodimers: a DQ heterodimer, encoded by DQA1*0501, DQB1*0201 and/or a DR heterodimer, encoded by the nonpolymorphic gene DRA and the DRB4 gene. Quantifying the relative penetrances of all...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Child
Share to Child, Preschool

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genetics, Population

Share to Genotype

Share to Infant

Share to Models, Genetic

Source

Identifiers

PMID: 9271713
DOI: 10.1002/(SICI)1098-2272(1997)14:4<413::AID-GEPI6>3.0.CO;2-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Synergistic effect of two HLA heterodimers in the susceptibility to celiac disease in Tunisia.PMID 9271713Read ↗

High risk genotypes for celiac disease.Semantic proximity Read ↗

HLA susceptibility genes in celiac disease: genetic mapping and role in pathogenesis.Semantic proximity Read ↗

Different dose effect of HLA-DQ alpha beta heterodimers in insulin-dependent diabetes mellitus and celiac disease susceptibility.Semantic proximity Read ↗

Dose effect of cis- and trans-encoded HLA-DQ alpha beta heterodimers in IDDM susceptibility.Semantic proximity Read ↗

HLA and celiac disease susceptibility: new genetic factors bring open questions about the HLA influence and gene-dosage effects.Semantic proximity Read ↗

Risk variation in celiac disease in a population from Southern Spain: evaluating the influence of the DQB1*02:02 allele frequency.Semantic proximity Read ↗

HLA-DQ relative risks for coeliac disease in European populations: a study of the European Genetics Cluster on Coeliac Disease.Semantic proximity Read ↗

A gene dosage effect of the DQA1∗0501/DQB1∗0201 allelic combination influences the clinical heterogeneity of celiac diseaseSemantic proximity Read ↗

T lymphocyte recognition of a celiac disease-associated cis- or trans-encoded HLA-DQ alpha/beta-heterodimer.Semantic proximity Read ↗

On the HLA-DQ(alpha 1*0501, beta 1*0201)-associated susceptibility in celiac disease: a possible gene dosage effect of DQB1*0201.Semantic proximity Read ↗

HLA types in celiac disease patients not carrying the DQA1*05-DQB1*02 (DQ2) heterodimer: results from the European Genetics Cluster on Celiac Disease.Semantic proximity Read ↗

HLA-DQ2.5 genes associated with celiac disease risk are preferentially expressed with respect to non-predisposing HLA genes: Implication for anti-gluten T cell response.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.