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Article

Using a mutual information-based site transition network to map the genetic evolution of influenza A/H3N2 virus.

Bioinformatics (Oxford, England) - 15 Sept 2009

Xia Zhen, Jin Gulei, Zhu Jun, Zhou Ruhong

Abstract excerpt

MOTIVATION: Mapping the antigenic and genetic evolution pathways of influenza A is of critical importance in the vaccine development and drug design of influenza virus. In this article, we have analyzed more than 4000 A/H3N2 hemagglutinin (HA) sequences from 1968 to 2008 to model the evolutionary path of the influenza virus, which allows us to predict its future potential drifts with specific mutations. RESULTS:...

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Source

Identifiers

PMID: 19706746
DOI: 10.1093/bioinformatics/btp423

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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