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Article

Changed epitopes drive the antigenic drift for influenza A (H3N2) viruses.

BMC bioinformatics - 15 Feb 2011

Huang Jhang-Wei, Yang Jinn-Moon

Abstract excerpt

BACKGROUND: In circulating influenza viruses, gradually accumulated mutations on the glycoprotein hemagglutinin (HA), which interacts with infectivity-neutralizing antibodies, lead to the escape of immune system (called antigenic drift). The antibody recognition is highly correlated to the conformation change on the antigenic sites (epitopes), which locate on HA surface. To quantify a changed epitope for escaping...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21342562
DOI: 10.1186/1471-2105-12-S1-S31
PMCID: PMC3044287

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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