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Article

Adenosine A 2A receptor deficiency reduces striatal glutamate outflow and attenuates brain injury induced by transient focal cerebral ischemia in mice.

Brain research - 10 Nov 2009

Gui Li, Duan Wei, Tian Hong, Li Chuanming, Zhu Jie, Chen Jiang-Fan, Zheng Jian

Abstract excerpt

Recent studies have demonstrated that adenosine A(2A) receptor (A(2A)R) inactivation protects against brain injury caused by cerebral ischemia in various animal models. However, the underlying mechanisms remain to be fully elucidated. We examined the effect A(2A)R genetic inactivation on extracellular glutamate in the striatum and its relationship to the neuroprotection afforded by A(2A)R inactivation following...

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Identifiers

PMID: 19703429
DOI: 10.1016/j.brainres.2009.08.050

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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