Article
Enhanced neuronal death from focal ischemia in AMPA-receptor transgenic mice.
Brain research. Molecular brain research - 15 Dec 1997
Le D, Das S, Wang Y F, Yoshizawa T, Sasaki Y F, Takasu M, Nemes A, Mendelsohn M, Dikkes P, Lipton S A, Nakanishi N
Abstract excerpt
Excitatory amino acid (EAA) receptors play an important role in neuronal cell death in acute cerebral ischemia. Blocking the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) subtype of EAA receptor has been shown to reduce cell death in global cerebral ischemia. However their role in f...
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