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[Effects of lidocaine on brain damage induced by transient global cerebral ischemia in mice of different apolipoprotein E genotypes].

Zhonghua yi xue za zhi - 21 Dec 2005

Song Ping-ping, Wang Dong-xin, Wang Pei-yu

Abstract excerpt

OBJECTIVE: To evaluate the effects of lidocaine on changes of neuropathological outcome as well as the learning and memory abilities induced by transient global cerebral ischemia in mice of different apolipoprotein E genotypes. METHODS: Transient global ischemia was induced by bilateral common carotid arteries occlusion (BCCAO) for a period of 17 minutes. Healthy male C57BL/6J wild-type mice (C57 mice) and...

Topics

Anesthetics, Local
Animals
Apolipoproteins E
Brain
Genotype
Injections, Intraperitoneal
Ischemic Attack, Transient
Lidocaine
Male
Maze Learning
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Inbred C57BL

Mice, Knockout

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Identifiers

PMID: 16409860

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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