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Article

Enhanced neurodegeneration after a high dose of methamphetamine in adenosine A3 receptor null mutant mice.

Neuroscience - 27 Oct 2011

Shen H, Luo Y, Yu S-J, Wang Y

Abstract excerpt

Previous reports have indicated that adenosine A3 receptor (A3R) knockout mice are more sensitive to ischemic or hypoxic brain injury. The purpose of this study was to examine if suppression of A3R expression is associated with increase in sensitivity to injury induced by a high dose of methamphetamine (Meth). Adult male A3R null mutant (-/-) mice and their controls (+/+) were injected with four doses (2 h apart)...

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Identifiers

PMID: 21867746
DOI: 10.1016/j.neuroscience.2011.08.013
PMCID: PMC3222939

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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