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Article

Neuroprotection in ischemic mouse brain induced by stem cell-derived brain implants.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism - 1 May 2007

Pignataro Giuseppe, Studer Francesca E, Wilz Andrew, Simon Roger P, Boison Detlev

Abstract excerpt

Protective mechanisms of the brain may reduce the extent of injury after focal cerebral ischemia. Here, we explored in a mouse model of focal cerebral ischemia potential synergistic neuroprotective effects of two mediators of neuroprotection: (i) neuronal or glial precursor cells and (ii) the inhibitory neuromodulator adenosine. Embryonic stem (ES) cells, engineered to release adenosine by biallelic disruption of...

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Identifiers

PMID: 17119544
DOI: 10.1038/sj.jcbfm.9600422

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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