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Article

Chromosomal abnormalities and novel disease-related regions in progression from Barrett's esophagus to esophageal adenocarcinoma.

International journal of cancer - 15 Nov 2009

Akagi Tadayuki, Ito Tetsuo, Kato Motohiro, Jin Zhe, Cheng Yulan, Kan Takatsugu, Yamamoto Go, Olaru Alexandru, Kawamata Norihiko, Boult Jessica, Soukiasian Harmik J, Miller Carl W, Ogawa Seishi, Meltzer Stephen J, Koeffler H Phillip

Abstract excerpt

Barrett's esophagus (BE) is a metaplastic condition caused by chronic gastroesophageal reflux which represents an early step in the development of esophageal adenocarcinoma (EAC). Single-nucleotide polymorphism microarray (SNP-chip) analysis is a novel, precise, high-throughput approach to examine genomic alterations in neoplasia. Using 250K SNP-chips, we examined the neoplastic progression of BE to EAC, studying...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19670330
DOI: 10.1002/ijc.24620
PMCID: PMC2766567

Genes

BNC2
ERBB2
RARA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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