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Article

Genome-wide analysis of genetic alterations in Barrett's adenocarcinoma using single nucleotide polymorphism arrays.

Laboratory investigation; a journal of technical methods and pathology - 1 Apr 2009

Wiech Thorsten, Nikolopoulos Elisabeth, Weis Roland, Langer Rupert, Bartholomé Kilian, Timmer Jens, Walch Axel K, Höfler Heinz, Werner Martin

Abstract excerpt

We performed genome-wide analysis of copy-number changes and loss of heterozygosity (LOH) in Barrett's esophageal adenocarcinoma by single nucleotide polymorphism (SNP) microarrays to identify associated genomic alterations. DNA from 27 esophageal adenocarcinomas and 14 matching normal tissues was subjected to SNP microarrays. The data were analyzed using dChipSNP software. Copy-number changes occurring in at...

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Source

Identifiers

PMID: 18663352
DOI: 10.1038/labinvest.2008.67

Genes

SOX7
CDH20
CST4
FHIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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