Article
Chromosomal instability and copy number alterations in Barrett's esophagus and esophageal adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 May 2009
Paulson Thomas G, Maley Carlo C, Li Xiaohong, Li Hongzhe, Sanchez Carissa A, Chao Dennis L, Odze Robert D, Vaughan Thomas L, Blount Patricia L, Reid Brian J
Abstract excerpt
PURPOSE: Chromosomal instability, as assessed by many techniques, including DNA content aneuploidy, loss of heterozygosity, and comparative genomic hybridization, has consistently been reported to be common in cancer and rare in normal tissues. Recently, a panel of chromosome instability biomarkers, including loss of heterozygosity and DNA content, has been reported to identify patients at high and low risk of...
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