Article
Genomic analyses reveal FAM84B and the NOTCH pathway are associated with the progression of esophageal squamous cell carcinoma.
GigaScience - 1 Jan 2016
Cheng Caixia, Cui Heyang, Zhang Ling, Jia Zhiwu, Song Bin, Wang Fang, Li Yaoping, Liu Jing, Kong Pengzhou, Shi Ruyi, Bi Yanghui, Yang Bin, Wang Juan, Zhao Zhenxiang, Zhang Yanyan, Hu Xiaoling, Yang Jie, He Chanting, Zhao Zhiping, Wang Jinfen, Xi Yanfeng, Xu Enwei, Li Guodong, Guo Shiping, Chen Yunqing, Yang Xiaofeng, Chen Xing, Liang Jianfang, Guo Jiansheng, Cheng Xiaolong, Wang Chuangui, Zhan Qimin, Cui Yongping
Abstract excerpt
BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is the sixth most lethal cancer worldwide and the fourth most lethal cancer in China. Genomic characterization of tumors, particularly those of different stages, is likely to reveal additional oncogenic mechanisms. Although copy number alterations and somatic point mutations associated with the development of ESCC have been identified by array-based...
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