Article
A study of mitochondrial DNA D-loop mutations and p53 status in nonmelanoma skin cancer.
The British journal of dermatology - 1 Nov 2009
Prior S L, Griffiths A P, Lewis P D
Abstract excerpt
BACKGROUND: Mitochondrial DNA (mtDNA) displacement-loop (D-loop) mutations have previously demonstrated potential as smoking-induced biomarkers in oral squamous cell carcinoma (SCC). Additionally, they have been observed in SCC and basal cell carcinoma of nonmelanoma skin cancer (NMSC). However, they have not been examined in the SCC precursor lesions, Bowen disease or actinic keratosis. OBJECTIVES: Here, we...
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