Article
Mitochondrial D310 D-Loop instability and histological subtypes in radiation-induced cutaneous basal cell carcinomas.
Journal of dermatological science - 1 Jan 2014
Boaventura Paula, Pereira Dina, Mendes Adélia, Batista Rui, da Silva André Ferreira, Guimarães Isabel, Honavar Mrinalini, Teixeira-Gomes José, Lopes José Manuel, Máximo Valdemar, Soares Paula
Abstract excerpt
BACKGROUND: Basal cell carcinoma (BCC) is the most frequent skin cancer. An elevated prevalence of BCC has been associated with radiation, namely after the Tinea capitis epilation treatment, being these tumors described as more aggressive. Mitochondrial DNA (mtDNA) mutations have been reported in many human tumors, but their occurrence in BCC is poorly documented. OBJECTIVE: The purpose of this work was to...
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