Mitochondrial DNA mutations in light-associated skin tumors.

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Article

Mitochondrial DNA mutations in light-associated skin tumors.

Anticancer research - 1 Jan 2000

Yang Jen-Hung, Lee Hsin-Chen, Chung Jing-Gung, Wei Yau-Huei

Abstract excerpt

Mutations of mitochondrial DNA (mtDNA) have been proposed to be involved in carcinogenesis. In this study, we applied the polymerase chain reaction techniques to investigate the frequency of occurrence and proportion of mtDNA with length mutations (deletions and tandem duplications) in light-associated skin tumors (actinic keratosis, AK; basal cell carcinoma, BCC; and squamous cell carcinoma, SCC) in aged...

Topics

Aged
Aged, 80 and over
Carcinoma, Basal Cell
Carcinoma, Squamous Cell
DNA, Mitochondrial
Humans
Keratosis
Middle Aged
Mutation
Polymerase Chain Reaction
Skin Neoplasms
Sunlight

Source

Open in PubMed

Identifiers

PMID: 15274351

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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