Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of hepatitis C virus core protein multimerization and membrane envelopment: revelation of a cascade of core-membrane interactions.

Journal of virology - 1 Oct 2009

Ai Li-Shuang, Lee Yu-Wen, Chen Steve S-L

Abstract excerpt

The molecular basis underlying hepatitis C virus (HCV) core protein maturation and morphogenesis remains elusive. We characterized the concerted events associated with core protein multimerization and interaction with membranes. Analyses of core proteins expressed from a subgenomic system showed that the signal sequence located between the core and envelope glycoprotein E1 is critical for core association with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aspartic Acid Endopeptidases
Share to Endosomes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ketones

Share to Microscopy, Confocal

Share to Protein Multimerization

Share to Protein Sorting Signals

Share to Subcellular Fractions

Share to Viral Core Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 19605478
DOI: 10.1128/JVI.00066-09
PMCID: PMC2748039

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of hepatitis C virus core protein multimerization and membrane envelopment: revelation of a cascade of core-membrane interactions.PMID 19605478Read ↗

The acidic domain of the hepatitis C virus NS4A protein is required for viral assembly and envelopment through interactions with the viral E1 glycoprotein.Semantic proximity Read ↗

Core protein cleavage by signal peptide peptidase is required for hepatitis C virus-like particle assembly.Semantic proximity Read ↗

Hepatitis C Virus p7 is Critical for Capsid Assembly and EnvelopmentSemantic proximity Read ↗

Maturation of hepatitis C virus core protein by signal peptide peptidase is required for virus production.Semantic proximity Read ↗

Characterization of hepatitis C virus intra- and intergenotypic chimeras reveals a role of the glycoproteins in virus envelopment.Semantic proximity Read ↗

Early steps of the hepatitis C virus life cycleSemantic proximity Read ↗

Hepatitis C Virus Envelope Glycoprotein E1 Forms Trimers at the Surface of the Virion.Semantic proximity Read ↗

Adaptive mutations promote hepatitis C virus assembly by accelerating core translocation to the endoplasmic reticulum.Semantic proximity Read ↗

The amino-terminus of the hepatitis C virus (HCV) p7 viroporin and its cleavage from glycoprotein E2-p7 precursor determine specific infectivity and secretion levels of HCV particle types.Semantic proximity Read ↗

Intramembrane processing by signal peptide peptidase regulates the membrane localization of hepatitis C virus core protein and viral propagation.Semantic proximity Read ↗

A genetic interaction between the core and NS3 proteins of hepatitis C virus is essential for production of infectious virus.Semantic proximity Read ↗

The potential of signal peptide peptidase as a therapeutic target for hepatitis C.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.