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Article

A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion.

Diabetes - 1 Oct 2009

Jonsson Anna, Isomaa Bo, Tuomi Tiinamaija, Taneera Jalal, Salehi Albert, Nilsson Peter, Groop Leif, Lyssenko Valeriya

Abstract excerpt

OBJECTIVE: Two independent genome-wide association studies for type 2 diabetes in Japanese subjects have recently identified common variants in the KCNQ1 gene that are strongly associated with type 2 diabetes. Here we studied whether a common variant in KCNQ1 would influence BMI as well as insulin secretion and action and predict future type 2 diabetes in subjects from Sweden and Finland. RESEARCH DESIGN AND...

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Source

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Identifiers

PMID: 19584308
DOI: 10.2337/db09-0246
PMCID: PMC2750226

Genes

KCNQ1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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