Article
Variations in KCNQ1 are associated with type 2 diabetes and beta cell function in a Chinese population.
Diabetologia - 1 Jul 2009
Hu C, Wang C, Zhang R, Ma X, Wang J, Lu J, Qin W, Bao Y, Xiang K, Jia W
Abstract excerpt
AIMS/HYPOTHESIS: Recent genome-wide association studies in East Asian populations reported that single nucleotide polymorphisms (SNPs) in KCNQ1 are associated with type 2 diabetes. The aim of this study was to validate this finding in a Chinese population. METHODS: We genotyped four SNPs, rs2074196, rs2237892, rs2237895 and rs2237897, in a group of 3,503 Shanghai Chinese individuals, comprising 1,769 type 2...
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