Article
Strong parent-of-origin effects in the association of KCNQ1 variants with type 2 diabetes in American Indians.
Diabetes - 1 Aug 2013
Hanson Robert L, Guo Tingwei, Muller Yunhua L, Fleming Jamie, Knowler William C, Kobes Sayuko, Bogardus Clifton, Baier Leslie J
Abstract excerpt
Parent-of-origin effects were observed in an Icelandic population for several genetic variants associated with type 2 diabetes, including those in KLF14 (rs4731702), MOB2 (rs2334499), and KCNQ1 (rs2237892, rs231362). We analyzed parent-of-origin effects for these variants, along with two others in KCNQ1 identified in previous genome-wide association studies (rs2237895, ), in 7,351 Pima Indians from 4,549...
