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Article

Poor survival associated with the BRAF V600E mutation in microsatellite-stable colon cancers.

Cancer research - 15 Jul 2005

Samowitz Wade S, Sweeney Carol, Herrick Jennifer, Albertsen Hans, Levin Theodore R, Murtaugh Maureen A, Wolff Roger K, Slattery Martha L

Abstract excerpt

The BRAF V600E mutation has been associated with microsatellite instability and the CpG island methylator phenotype (CIMP) in colon cancer. We evaluated a large population-based sample of individuals with colon cancer to determine its relationship to survival and other clinicopathologic variables. The V600E BRAF mutation was seen in 5% (40 of 803) of microsatellite-stable tumors and 51.8% (43 of 83) of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16024606
DOI: 10.1158/0008-5472.CAN-05-0404

Genes

BRAF

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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