Article
Microsatellite instability and survival in rectal cancer.
Cancer causes & control : CCC - 1 Nov 2009
Samowitz Wade S, Curtin Karen, Wolff Roger K, Tripp Sheryl R, Caan Bette J, Slattery Martha L
Abstract excerpt
OBJECTIVE: High levels of microsatellite instability (MSI-H) have been associated in many studies with improved prognosis in colon cancer. Very few studies have evaluated the effect of MSI-H on rectal cancer survival. We assessed MSI-H and other genetic and epigenetic changes on survival of 990 individuals diagnosed with first primary rectal cancer. METHODS: MSI was assessed primarily by instability in the...
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