Microsatellite instability and survival in rectal cancer.

doi:10.1007/s10552-009-9410-3

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Article

Microsatellite instability and survival in rectal cancer.

Cancer causes & control : CCC - 1 Nov 2009

Samowitz Wade S, Curtin Karen, Wolff Roger K, Tripp Sheryl R, Caan Bette J, Slattery Martha L

Abstract excerpt

OBJECTIVE: High levels of microsatellite instability (MSI-H) have been associated in many studies with improved prognosis in colon cancer. Very few studies have evaluated the effect of MSI-H on rectal cancer survival. We assessed MSI-H and other genetic and epigenetic changes on survival of 990 i...

Topics

Adaptor Proteins, Signal Transducing
Adult
Aged
Cadherins
Carrier Proteins
Colorectal Neoplasms, Hereditary Nonpolyposis
CpG Islands
Cyclin-Dependent Kinase Inhibitor p16
DNA Methylation
Female
Humans
Immunohistochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Kaplan-Meier Estimate

Male

Microsatellite Instability

Middle Aged

Mutation

Neoplasm Staging

Source

Open in PubMed Open full text

Identifiers

PMID: 19669908
DOI: 10.1007/s10552-009-9410-3
PMCID: PMC2895463

Genes

BRAF
MLH1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-19669908-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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