The Val/Met functional polymorphism in COMT confers susceptibility to bipolar disorder: evidence from an association study and a meta-analysis.

doi:10.1007/s00702-009-0260-7

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Article

The Val/Met functional polymorphism in COMT confers susceptibility to bipolar disorder: evidence from an association study and a meta-analysis.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Oct 2009

Zhang Zhao, Lindpaintner Klaus, Che Ronglin, He Zangdong, Wang Peng, Yang Ping, Feng Guoyin, He Lin, Shi Yongyong

Abstract excerpt

The COMT gene is considered as one of the prominent candidate genes for susceptibility to BP, and most studies focused a functional polymorphism in the gene: the Val/Met polymorphism (rs4680). However, results from these studies are sometimes contradictory, due to small sample size or heterogeneity. In this study, we first investigate the possible association between the Val/Met polymorphism in COMT and bipolar...

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PMID: 19578924
DOI: 10.1007/s00702-009-0260-7

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COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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