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Article

Association analysis of COMT polymorphisms and schizophrenia in a Chinese Han population: a case-control study.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jun 2007

Yu Rui, Zhang Xian-Ning, Huang Xiao-Xiao, Ding Shi-Ping, Li Ji-Cheng

Abstract excerpt

Schizophrenia is a common disease with complex mode of inheritance; great efforts have been made to identify the susceptible genes. Catechol-O-methyltransferase (COMT) gene has long been considered as a candidate gene mainly because of two reasons: First, it encodes a key dopamine catabolic enzyme. Second, it maps to the velocardiofacial syndrome (VCFS) region of chromosome 22q11, which is associated with...

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Source

Identifiers

PMID: 17427186
DOI: 10.1002/ajmg.b.30487

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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